THE J HEALTHCARE INITIATIVE
Fluclotizolam
Found in:
Fentanyl, BZD
Type/Reason added:
DBZD
Relative Potency:
N/A
Treatment Options
Supportive Care:
Airway protection and respiratory monitoring.
Antidote:
Flumazenil may be administered in emergencies, though it can precipitate withdrawal in dependent users.
Pharmacokinetics and Dynamics
Metabolism:
Fluclotizolam is metabolized in the liver, likely through the cytochrome P450 enzyme system, specifically CYP3A4. Its metabolites are excreted primarily via the urine.
Drug-Drug Interactions:
Fluclotizolam has dangerous interactions with other depressants, including alcohol, opioids, and other sedative drugs, which significantly increase the risk of respiratory depression and fatal overdose. Medications that inhibit or induce CYP3A4 can alter its metabolism and effects.
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