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Bromazolam

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Found in: 


Fentanyl, BZD

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Type/Reason added: 


Short acting DBZD

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Relative Potency: 


N/A

Treatment Options

Supportive Care: 

In cases of overdose, medical intervention is required, including securing the airway, providing respiratory support, and monitoring cardiovascular function.

Antidote: 

Flumazenil, a benzodiazepine receptor antagonist, can be used as an antidote, but its use is typically reserved for specific cases due to the risk of precipitating withdrawal or seizures in dependent individuals.

Pharmacokinetics and Dynamics

Metabolism: 

Bromazolam is metabolized in the liver, likely through the CYP450 enzyme system, though its metabolic pathways are not as well-documented as more common benzodiazepines.

Drug-Drug Interactions: 

There is a high potential for dangerous interactions with other CNS depressants, including alcohol, opioids, and other benzodiazepines, which can significantly increase the risk of sedation, respiratory depression, and overdose.

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